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Fantasy football injury report: Week 6, 2026

Injury notes from this week's briefing, ordered from Out to Questionable. Statuses change daily, so check the daily briefing before kickoff. Last updated October 18, 2026, 8:30 AM ET.

Week 6 injuries, most serious first

Jalen Hurts

QB · PHI

Jalen Hurts: ruled OUT for Week 6 (calf blood clot); Tanner McKee starts

The Eagles ruled Hurts out Sunday against Carolina with a calf blood clot, so Tanner McKee starts. DeVonta Smith was a full participant Friday and is not on the report, but he is a risk/reward WR3 with a backup QB; Dallas Goedert is the pass-catcher to trust.

Status: Out · Confidence: high

Source: cbssports.com · espn.in · nfl.com

Saquon Barkley

RB · PHI

Saquon Barkley: ruled OUT again (hamstring); Dameon Pierce leads the backfield

Barkley did not practice all week and is officially out for Week 6. Dameon Pierce is expected to lead a battered Philadelphia backfield.

Status: Out · Confidence: high

Source: si.com · nfl.com · cbssports.com

Breece Hall

RB · NYJ

Breece Hall: ruled OUT at New England (quad); Braelon Allen is the Jets' RB to use

Hall did not practice Wednesday through Friday and is officially out. Braelon Allen is the Jets back to start if you need rushing volume.

Status: Out · Confidence: high

Source: nfl.com · sports.yahoo.com · cbssports.com

Lamar Jackson

QB · BAL

Lamar Jackson: ruled OUT again (ankle); Tyler Huntley starts vs Cleveland

Jackson has not practiced since the injury and is officially out for a second straight week. Huntley starts; stream Jordan Love, Kirk Cousins or Tyler Shough if you need a one-QB answer.

Status: Out · Confidence: high

Source: cbssports.com · espn.in · nfl.com

David Montgomery

RB · HOU

David Montgomery: inactive in London (groin); Woody Marks leads Houston

Houston declared Montgomery inactive for the 9:30am ET game at Jacksonville after he missed every practice. Marks handles the bulk of the backfield work.

Status: Out · Confidence: high

Source: nbcsports.com · fantasypros.com · nfl.com

TreVeyon Henderson

RB · NE

TreVeyon Henderson: likely to play vs the Jets, but on a pitch count

Rapoport reports Henderson will likely play through his high-ankle sprain, though a limited workload is expected. Treat him as a high-risk FLEX and confirm at the 11:30am ET inactives.

Status: Questionable · Confidence: medium

Source: nbcsports.com · sports.yahoo.com · nfl.com

Caleb Williams

QB · CHI

Caleb Williams: expected to start at Atlanta after a full week of practice

Williams practiced in full all week on his hamstring and is expected back under center. Start him as a back-end QB1 against the Falcons.

Status: Questionable · Confidence: high

Source: cbssports.com · nfl.com

A.J. Brown

WR · NE

A.J. Brown: activated off IR and expected to play vs the Jets

New England activated Brown on Saturday and he is expected to make his first appearance since Week 1. Start him as a WR2 with some snap-count risk in his return.

Status: Questionable · Confidence: high

Source: nfl.com · patriots.com · fantasypros.com

Alvin Kamara

RB · NO

Alvin Kamara: expected to play at the Giants despite the back issue

Kamara is questionable after three limited practices but is expected to play. His workload has been light lately, so he is a FLEX play with a fallback ready at inactives.

Status: Questionable · Confidence: medium

Source: draftsharks.com · sports.yahoo.com · nfl.com

Frequently asked questions

Which fantasy players are out in Week 6?

Listed OUT in this week's briefing: Jalen Hurts (QB, PHI); Saquon Barkley (RB, PHI); Breece Hall (RB, NYJ); Lamar Jackson (QB, BAL); David Montgomery (RB, HOU).

Where do I see the latest injury news?

The daily fantasy briefing on this site updates through the week with game-day injury and lineup news.

How do I see injuries on my own roster?

Sync your ESPN or Sleeper team. The My Week report flags hurt starters first and suggests a swap from the week's start calls.

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