Injury notes from this week's briefing, ordered from Out to Questionable. Statuses change daily, so check the daily briefing before kickoff. Last updated October 18, 2026, 8:30 AM ET.
Week 6 injuries, most serious first
Jalen Hurts
QB · PHI
Jalen Hurts: ruled OUT for Week 6 (calf blood clot); Tanner McKee starts
The Eagles ruled Hurts out Sunday against Carolina with a calf blood clot, so Tanner McKee starts. DeVonta Smith was a full participant Friday and is not on the report, but he is a risk/reward WR3 with a backup QB; Dallas Goedert is the pass-catcher to trust.
Status: Out · Confidence: high
Source: cbssports.com · espn.in · nfl.com
Saquon Barkley
RB · PHI
Saquon Barkley: ruled OUT again (hamstring); Dameon Pierce leads the backfield
Barkley did not practice all week and is officially out for Week 6. Dameon Pierce is expected to lead a battered Philadelphia backfield.
Status: Out · Confidence: high
Source: si.com · nfl.com · cbssports.com
Breece Hall
RB · NYJ
Breece Hall: ruled OUT at New England (quad); Braelon Allen is the Jets' RB to use
Hall did not practice Wednesday through Friday and is officially out. Braelon Allen is the Jets back to start if you need rushing volume.
Status: Out · Confidence: high
Source: nfl.com · sports.yahoo.com · cbssports.com
Lamar Jackson
QB · BAL
Lamar Jackson: ruled OUT again (ankle); Tyler Huntley starts vs Cleveland
Jackson has not practiced since the injury and is officially out for a second straight week. Huntley starts; stream Jordan Love, Kirk Cousins or Tyler Shough if you need a one-QB answer.
Status: Out · Confidence: high
Source: cbssports.com · espn.in · nfl.com
David Montgomery
RB · HOU
David Montgomery: inactive in London (groin); Woody Marks leads Houston
Houston declared Montgomery inactive for the 9:30am ET game at Jacksonville after he missed every practice. Marks handles the bulk of the backfield work.
Status: Out · Confidence: high
Source: nbcsports.com · fantasypros.com · nfl.com
TreVeyon Henderson
RB · NE
TreVeyon Henderson: likely to play vs the Jets, but on a pitch count
Rapoport reports Henderson will likely play through his high-ankle sprain, though a limited workload is expected. Treat him as a high-risk FLEX and confirm at the 11:30am ET inactives.
Status: Questionable · Confidence: medium
Source: nbcsports.com · sports.yahoo.com · nfl.com
Caleb Williams
QB · CHI
Caleb Williams: expected to start at Atlanta after a full week of practice
Williams practiced in full all week on his hamstring and is expected back under center. Start him as a back-end QB1 against the Falcons.
Status: Questionable · Confidence: high
Source: cbssports.com · nfl.com
A.J. Brown
WR · NE
A.J. Brown: activated off IR and expected to play vs the Jets
New England activated Brown on Saturday and he is expected to make his first appearance since Week 1. Start him as a WR2 with some snap-count risk in his return.
Status: Questionable · Confidence: high
Source: nfl.com · patriots.com · fantasypros.com
Alvin Kamara
RB · NO
Alvin Kamara: expected to play at the Giants despite the back issue
Kamara is questionable after three limited practices but is expected to play. His workload has been light lately, so he is a FLEX play with a fallback ready at inactives.
Status: Questionable · Confidence: medium
Source: draftsharks.com · sports.yahoo.com · nfl.com